Tuesday, September 22, 2026

Opponents own a strong .808 OPS against Yusei Kikuchi this season, and the Athletics will be happy to face him back at home after averaging just 2 runs per game on their road trip last week. The Angels are also in a strong position to find success at the plate going up against an inexperienced Brady Basso and a weak Athletics bullpen.

The Guardians have won 5 in a row, and they need to keep stacking wins this week. Boston is sitting pretty, and they might limit Tolle's pitches as they get ready for the postseason. Motivation is on the side of the Guardians, and I will take that.

The Giants’ defense looked good against Dallas, but they don’t know the Rams like the 49ers do. Nor does John Harbaugh. Expect Los Angeles to score immediately, which means the Giants will be chasing. If New York can get to 20, this total should soar over 50.

After beating the Cowboys in their opener, the Giants now need to refocus and travel across the country to face an angry Matthew Stafford and company. On paper, the Rams still own one of the most impressive skill groups in the NFL. We like regression to swing this in favor of LA.

Likely exploded for eight receptions, 78 yards and two touchdowns in the win over the Cowboys, and with it being so early in the season, the markets may not have caught up to his usage just yet. This 4.5 reception mark at even money is a steal of a price.

The Giants’ defense looked good against Dallas, but they don’t know the Rams like the 49ers do. Nor does John Harbaugh. Expect Los Angeles to score immediately, which means the Giants will be chasing. If New York can get to 20, this total should soar over 50.

After beating the Cowboys in their opener, the Giants now need to refocus and travel across the country to face an angry Matthew Stafford and company. On paper, the Rams still own one of the most impressive skill groups in the NFL. We like regression to swing this in favor of LA.

There were very few bright spots for the Rams in Week 1, but Blake Corum stood out immediately. He was explosive and hit the gap with confidence, resulting in 10 carries for 54 yards. He should find quite a bit of success against a weak Giants interior defensive line.

The Giants’ defense looked good against Dallas, but they don’t know the Rams like the 49ers do. Nor does John Harbaugh. Expect Los Angeles to score immediately, which means the Giants will be chasing. If New York can get to 20, this total should soar over 50.

After beating the Cowboys in their opener, the Giants now need to refocus and travel across the country to face an angry Matthew Stafford and company. On paper, the Rams still own one of the most impressive skill groups in the NFL. We like regression to swing this in favor of LA.

There were very few bright spots for the Rams in Week 1, but Blake Corum stood out immediately. He was explosive and hit the gap with confidence, resulting in 10 carries for 54 yards. He should find quite a bit of success against a weak Giants interior defensive line.

DJ Herz has not pitched in the majors since April 2025. River Ryan hasn’t pitched in the majors since 2024 and will be making his Tigers debut. With that in mind, both starting pitchers should be vulnerable in this one at that should lead to plenty of runs.

The Giants’ defense looked good against Dallas, but they don’t know the Rams like the 49ers do. Nor does John Harbaugh. Expect Los Angeles to score immediately, which means the Giants will be chasing. If New York can get to 20, this total should soar over 50.

Zack Wheeler's last four starts have all lasted 6.0 innings or more, and he did not give up more than one earned run in each start. These teams have played three times already this season, two of the three games went under Tuesday’s projected game total.

DJ Herz has not pitched in the majors since April 2025. River Ryan hasn’t pitched in the majors since 2024 and will be making his Tigers debut. With that in mind, both starting pitchers should be vulnerable in this one at that should lead to plenty of runs.

Shane Baz is in shaky form and faces a Toronto lineup that scored five runs off him earlier this season. Trey Yesavage returns from injury after struggling in his only rehab outing. I favor runs from both sides.