Sunday, September 20, 2026
100 picks from Sunday, September 20, 2026. Results included where graded.
- UFC
Van @ Pantoja
UFC 331 Parlay featuring Van vs Pantoja 2by Matthew Lowrimore+309odds - NFL
New York Giants @ Los Angeles Rams
Over 47.5Best Bet Game Totals Pick
by Chris Farley-105odds - NFL
New York Giants @ Los Angeles Rams
Spread - Los Angeles Rams -6.5by Chris Farley-102odds - NFL
Indianapolis Colts @ Kansas City Chiefs
Over 46by Chris Farley-102odds - NFL
Seattle Seahawks @ Arizona Cardinals
Under 44.5by Caleb Wilfinger+108odds - NFL
Seattle Seahawks @ Arizona Cardinals
Spread - Arizona Cardinals +2.5by Caleb Wilfinger+113odds - NFL
Miami Dolphins @ San Francisco 49ers
Under 40.5by Sam Avellone+113odds - NFL
Miami Dolphins @ San Francisco 49ers
Spread - Miami Dolphins +14.5Point Spread Pick Underdog
by Sam Avellone+113odds - NFL
Washington Commanders @ Dallas Cowboys
Under 51.5by Aaron Taylor-110odds - NFL
Washington Commanders @ Dallas Cowboys
Spread - Dallas Cowboys -9.5Best Bet Point Spread Pick
by Aaron Taylor-113odds - NFL
Las Vegas Raiders @ Los Angeles Chargers
Spread - Los Angeles Chargers -2.5by Kevin Rogers+100odds - NFL
Las Vegas Raiders @ Los Angeles Chargers
Under 38.5by Kevin Rogers+104odds - NFL
Jacksonville Jaguars @ Denver Broncos
Over 38.5by Kevin Rogers-105odds - NFL
Jacksonville Jaguars @ Denver Broncos
Spread - Jacksonville Jaguars -2.5by Kevin Rogers-112odds - MLB
San Francisco Giants @ Los Angeles Dodgers
Under 6.5While the Dodgers offense has been in incredible form as of late, it’s hard to back a side with roughly 90% of public tickets riding the over in this case.
by Ryan Bunnell-102odds - UFC
Dei Pay D. Figueiredo @ P. Talbott
D. FigueiredoMoney Line
by Pickswise Analysts+490odds - NFL
Indianapolis Colts @ Kansas City Chiefs
OverShane Steichen specializes in offense and his group left much to be desired after a 23-point output (and just 251 yards) last Sunday. We doubt the Colts will depend on their defense to correct their woes
by Chris FarleyEVENodds - NFL
Indianapolis Colts @ Kansas City Chiefs
Spread - Indianapolis Colts +6The Colts enter this battle in a desperate mood and they’re getting over a touchdown of points to boot. There is a world where the new-look Chiefs pull away, but we also can’t handicap this matchup based on a one-game sample size, either. Buy low on Indianapolis and sell high on Kansas City.
by Chris Farley-110odds - NFL
Seattle Seahawks @ Arizona Cardinals
Under 41Both defenses are in good position to succeed and both offenses can be expected to lean into the running game, which should chew up plenty of clock and lead to an under.
by Caleb Wilfinger-105odds - NFL
Miami Dolphins @ San Francisco 49ers
Spread - Miami Dolphins +13On a normal week, I could see total domination from San Francisco. However, given the circumstances surrounding this game and the exorbitant price, I would have a very hard time betting someone else’s money on the Niners here, let alone mine.
by Sam Avellone-105odds - NFLwin
Pittsburgh Steelers @ New England Patriots
Under 23.5Neither offense showed much in Week 1, and the number here already reflects that, sitting among the lower totals on the board. I still think it's got room to come down further.
by Luke LindholmEVENodds - NFLloss
Pittsburgh Steelers @ New England Patriots
Spread - New England Patriots -17.5Home-field advantage at Gillette Stadium matters here. New England is desperate to avoid an 0-2 start, and I expect a sharper, more disciplined performance from a talented roster that simply beat itself in Week 1. I like the Patriots to clean up the turnovers and cover at home.
by Luke LindholmEVENodds - NFL
Cleveland Browns @ Tampa Bay Buccaneers
Under 48.5Cleveland’s defense should put up a better effort against a Bucs team that scored 20 or fewer points in three of its final four home contests of 2025, while the Tampa defense did not allow a Bengals TD last week without a turnover setting it up. A low-scoring contest beckons here.
by Kevin Rogers+140odds - NFL
Cleveland Browns @ Tampa Bay Buccaneers
Spread - Cleveland Browns +2.5Cleveland posted a humiliating effort in Week 1, while Tampa Bay dug themselves too big of a hole to climb out of. In this spot, the public will be all over the Bucs to bounce back, but let’s go with the Browns here getting a shade over a touchdown on the road.
by Kevin Rogers-105odds - NFLwin
Philadelphia Eagles @ Tennessee Titans
Over 43.5It did not happen last week, but you have to think that Tennessee QB Cam Ward will make some strides in his second year. This is the smallest total (39.5) of the entire week in the NFL.
by Ricky DimonEVENodds - NFLwin
Carolina Panthers @ Atlanta Falcons
Spread - Carolina Panthers -30.5Fortunately for the Panthers, the Falcons' offense won't resemble anything like what the Bears put on the field this past weekend. Atlanta's QB issues are probably too much to overcome.
by Ricky Dimon+1300odds - NFLwin
Cincinnati Bengals @ Houston Texans
Under 26.5The Bengals’ defense gave up just 60 yards to running backs against Tampa Bay. Last season, Cincinnati allowed a league-worst 119.2 yards to that position. Both these teams have strong over trends, but it’s hard to think that Houston’s defense gets lit up once again, and Cincinnati will likely not finish at +4 in the turnover department.
by Kevin Rogers-235odds - NFLloss
Cincinnati Bengals @ Houston Texans
Spread - Houston Texans +13.5The Bengals beat the Bucs last week but 24 of their 33 points came off turnovers, and the Texans should bounce back here after coming up just short against the Bills. Houston’s defense allowed the fewest yards per game last season and they should have some success in pacifying Joe Burrow.
by Kevin Rogers+270odds - NFLloss
Green Bay Packers @ New York Jets
Over 37.5The market is underrating the suddenly competent Jets offense, while the Packers should generate explosives against a questionable New York secondary. Take the over.
by Caleb Wilfinger+154odds - NFLloss
Green Bay Packers @ New York Jets
Spread - New York Jets -1.5Jordan Love is a whopping 0-8 against the spread when laying over a field goal on the road and the Jets are much improved following an infusion of talent into this roster over the offseason. Take the home underdog.
by Caleb Wilfinger+100odds - MLBwin
Washington Nationals @ St. Louis Cardinals
Over 7.5The Nationals are the third-highest scoring team in the MLB, averaging 5.1 runs per game. The Nationals will send Jake Irvin to the mound, who has an inflated 5.51 ERA in 96.1 innings this season.
by Jon Yaremko+124odds - MLBwin
Kansas City Royals @ Pittsburgh Pirates
Over 6.5Pittsburgh ranks fifth in baseball at 4.8 runs per game, while both bullpens have recorded 25 blown saves. Michael Wacha has pitched well, but the Pirates possess enough offense to challenge him and get to Kansas City's relief corps afterward. With Pittsburgh's pitching situation bullpen vulnerable yet leading the way, back the over in another value spot.
by Napier Montgomery-111odds - UFC
Dei Pay @ D. Figueiredo
P. TalbottComing Soon
by Pickswise Analysts-675odds - NFLwin
Pittsburgh Steelers @ New England Patriots
Under 26.5Neither offense showed much in Week 1, and the number here already reflects that, sitting among the lower totals on the board. I still think it's got room to come down further.
by Luke Lindholm-108odds - NFL
Cleveland Browns @ Tampa Bay Buccaneers
Under 38.5Cleveland’s defense should put up a better effort against a Bucs team that scored 20 or fewer points in three of its final four home contests of 2025, while the Tampa defense did not allow a Bengals TD last week without a turnover setting it up. A low-scoring contest beckons here.
by Kevin Rogers-113odds - NFLloss
Philadelphia Eagles @ Tennessee Titans
Over 44.5It did not happen last week, but you have to think that Tennessee QB Cam Ward will make some strides in his second year. This is the smallest total (39.5) of the entire week in the NFL.
by Ricky Dimon+117odds - NFLwin
Philadelphia Eagles @ Tennessee Titans
Spread - Philadelphia Eagles -3.5Tennessee opened with a terrible 23-10 home loss to the Jets in Week 1, suggesting that it is the worst team in the entire NFL -- or maybe the second-worst, ahead of Cleveland. Philadelphia (1-0) should roll.
by Ricky Dimon+117odds - NFLwin
Carolina Panthers @ Atlanta Falcons
Spread - Carolina Panthers -20.5Fortunately for the Panthers, the Falcons' offense won't resemble anything like what the Bears put on the field this past weekend. Atlanta's QB issues are probably too much to overcome.
by Ricky Dimon-107odds - NFLwin
Cincinnati Bengals @ Houston Texans
Under 32.5The Bengals’ defense gave up just 60 yards to running backs against Tampa Bay. Last season, Cincinnati allowed a league-worst 119.2 yards to that position. Both these teams have strong over trends, but it’s hard to think that Houston’s defense gets lit up once again, and Cincinnati will likely not finish at +4 in the turnover department.
by Kevin Rogers-110odds - NFLloss
Cincinnati Bengals @ Houston Texans
Spread - Houston Texans +6.5The Bengals beat the Bucs last week but 24 of their 33 points came off turnovers, and the Texans should bounce back here after coming up just short against the Bills. Houston’s defense allowed the fewest yards per game last season and they should have some success in pacifying Joe Burrow.
by Kevin Rogers+105odds - NFLwin
Green Bay Packers @ New York Jets
Over 30.5The market is underrating the suddenly competent Jets offense, while the Packers should generate explosives against a questionable New York secondary. Take the over.
by Caleb Wilfinger-108odds - NFLloss
Green Bay Packers @ New York Jets
Spread - New York Jets +2.5Jordan Love is a whopping 0-8 against the spread when laying over a field goal on the road and the Jets are much improved following an infusion of talent into this roster over the offseason. Take the home underdog.
by Caleb Wilfinger-104odds - MLBwin
Kansas City Royals @ Pittsburgh Pirates
Over 5.5Pittsburgh ranks fifth in baseball at 4.8 runs per game, while both bullpens have recorded 25 blown saves. Michael Wacha has pitched well, but the Pirates possess enough offense to challenge him and get to Kansas City's relief corps afterward. With Pittsburgh's pitching situation bullpen vulnerable yet leading the way, back the over in another value spot.
by Napier Montgomery+125odds - NFLwin
Pittsburgh Steelers @ New England Patriots
Under 34.5Neither offense showed much in Week 1, and the number here already reflects that, sitting among the lower totals on the board. I still think it's got room to come down further.
by Luke Lindholm-106odds - NFLwin
Pittsburgh Steelers @ New England Patriots
Spread - New England Patriots -12.5Home-field advantage at Gillette Stadium matters here. New England is desperate to avoid an 0-2 start, and I expect a sharper, more disciplined performance from a talented roster that simply beat itself in Week 1. I like the Patriots to clean up the turnovers and cover at home.
by Luke Lindholm-104odds - NFL
Cleveland Browns @ Tampa Bay Buccaneers
Under 39.5Cleveland’s defense should put up a better effort against a Bucs team that scored 20 or fewer points in three of its final four home contests of 2025, while the Tampa defense did not allow a Bengals TD last week without a turnover setting it up. A low-scoring contest beckons here.
by Kevin Rogers-104odds - NFL
Cleveland Browns @ Tampa Bay Buccaneers
Spread - Cleveland Browns +6.5Cleveland posted a humiliating effort in Week 1, while Tampa Bay dug themselves too big of a hole to climb out of. In this spot, the public will be all over the Bucs to bounce back, but let’s go with the Browns here getting a shade over a touchdown on the road.
by Kevin Rogers+113odds - NFLwin
New Orleans Saints @ Baltimore Ravens
Over 36.5Both of these teams put on a show in Week 1, and I don't see much reason to expect any different in Week 2. Baltimore hung 41 points on Indianapolis behind a fully operational Jackson-Henry combination, while New Orleans and Detroit combined for 61 points in their overtime thriller. That's two offenses trending in the same direction heading into Sunday.
by Luke Lindholm-105odds - NFLwin
New Orleans Saints @ Baltimore Ravens
Spread - New Orleans Saints +9.5New Orleans, meanwhile, is coming off a gut-punch of a Week 1 loss, falling 31-30 in overtime to Detroit after digging itself out of a 21-point hole. That comeback is exactly why I'm not ready to write the Saints off against a number this big.
by Luke Lindholm+104odds - NFLwin
Philadelphia Eagles @ Tennessee Titans
Over 41.5It did not happen last week, but you have to think that Tennessee QB Cam Ward will make some strides in his second year. This is the smallest total (39.5) of the entire week in the NFL.
by Ricky Dimon-102odds - NFLloss
Philadelphia Eagles @ Tennessee Titans
Spread - Philadelphia Eagles -12.5Tennessee opened with a terrible 23-10 home loss to the Jets in Week 1, suggesting that it is the worst team in the entire NFL -- or maybe the second-worst, ahead of Cleveland. Philadelphia (1-0) should roll.
by Ricky Dimon-110odds - NFLwin
Carolina Panthers @ Atlanta Falcons
Under 38.5Four of the last seven head-to-head encounters have produced no more than 40 points. Largely due to Atlanta's offense issues, another relatively low-scoring affair could be in the cards.
by Ricky Dimon-105odds - NFLwin
Carolina Panthers @ Atlanta Falcons
Spread - Carolina Panthers -10.5Fortunately for the Panthers, the Falcons' offense won't resemble anything like what the Bears put on the field this past weekend. Atlanta's QB issues are probably too much to overcome.
by Ricky Dimon+100odds - NFLwin
Cincinnati Bengals @ Houston Texans
Under 27.5The Bengals’ defense gave up just 60 yards to running backs against Tampa Bay. Last season, Cincinnati allowed a league-worst 119.2 yards to that position. Both these teams have strong over trends, but it’s hard to think that Houston’s defense gets lit up once again, and Cincinnati will likely not finish at +4 in the turnover department.
by Kevin Rogers+100odds - NFLwin
Green Bay Packers @ New York Jets
Over 36.5The market is underrating the suddenly competent Jets offense, while the Packers should generate explosives against a questionable New York secondary. Take the over.
by Caleb Wilfinger-104odds - NFLwin
Green Bay Packers @ New York Jets
Spread - New York Jets +6.5Jordan Love is a whopping 0-8 against the spread when laying over a field goal on the road and the Jets are much improved following an infusion of talent into this roster over the offseason. Take the home underdog.
by Caleb Wilfinger+117odds - MLBloss
Kansas City Royals @ Pittsburgh Pirates
Over 7.5Pittsburgh ranks fifth in baseball at 4.8 runs per game, while both bullpens have recorded 25 blown saves. Michael Wacha has pitched well, but the Pirates possess enough offense to challenge him and get to Kansas City's relief corps afterward. With Pittsburgh's pitching situation bullpen vulnerable yet leading the way, back the over in another value spot.
by Napier Montgomery+100odds - NFL
Seattle Seahawks @ Arizona Cardinals
Spread - Arizona Cardinals +4The Cardinals are clearly better than what their market expectations were prior to the season. Seattle's offense is not equipped to pull away from most teams without Sam Darnold at quarterback, and this should be a close contest.
by Caleb Wilfinger+100odds - NFL
Miami Dolphins @ San Francisco 49ers
Spread - Miami Dolphins +13.5On a normal week, I could see total domination from San Francisco. However, given the circumstances surrounding this game and the exorbitant price, I would have a very hard time betting someone else’s money on the Niners here, let alone mine.
by Sam Avellone-108odds - NFL
Las Vegas Raiders @ Los Angeles Chargers
Spread - Los Angeles Chargers -6.5The Chargers are 5-0 in the previous five meetings with the Raiders at SoFi Stadium, while covering the spread each time. This is a good spot to back the Bolts after their surprising Week 1 loss, as they take on a Raiders team they have owned recently.
by Kevin Rogers-105odds - NFL
Las Vegas Raiders @ Los Angeles Chargers
Under 43.5From 2021 through 2025, the Raiders and Chargers finished under the total at SoFi Stadium until last season’s over. This total is three points higher than last season’s matchup in Inglewood, so let’s take advantage and back the under.
by Kevin Rogers-102odds - NFL
Jacksonville Jaguars @ Denver Broncos
Over 45.5Bo Nix threw five more TD passes at home last season (15) than on the road, while putting up 600 more passing yards at home. Jacksonville has been able to put up points since the second half of last season, while Denver’s offense should put up a better performance at home after getting shut down at Kansas City.
by Kevin Rogers-102odds - NFL
Jacksonville Jaguars @ Denver Broncos
Spread - Jacksonville Jaguars +2.5The Broncos lost once in eight regular-season home games last season, which came to Jacksonville. The Jags posted a solid 6-2 road mark in 2025, which included blowing a 29-10 lead in a loss at Houston. The expectation is Denver should bounce back, but Jacksonville is playing with plenty of confidence and looks a solid road underdog.
by Kevin Rogers+106odds - NFLwin
Pittsburgh Steelers @ New England Patriots
Under 40.5Neither offense showed much in Week 1, and the number here already reflects that, sitting among the lower totals on the board. I still think it's got room to come down further.
by Luke Lindholm-111odds - NFLwin
Pittsburgh Steelers @ New England Patriots
Spread - New England Patriots -6.5Home-field advantage at Gillette Stadium matters here. New England is desperate to avoid an 0-2 start, and I expect a sharper, more disciplined performance from a talented roster that simply beat itself in Week 1. I like the Patriots to clean up the turnovers and cover at home.
by Luke Lindholm-109odds - NFL
Cleveland Browns @ Tampa Bay Buccaneers
Under 40.5Cleveland’s defense should put up a better effort against a Bucs team that scored 20 or fewer points in three of its final four home contests of 2025, while the Tampa defense did not allow a Bengals TD last week without a turnover setting it up. A low-scoring contest beckons here.
by Kevin Rogers-115odds - NFL
Cleveland Browns @ Tampa Bay Buccaneers
Spread - Cleveland Browns +9.5Cleveland posted a humiliating effort in Week 1, while Tampa Bay dug themselves too big of a hole to climb out of. In this spot, the public will be all over the Bucs to bounce back, but let’s go with the Browns here getting a shade over a touchdown on the road.
by Kevin Rogers-111odds - NFLloss
New Orleans Saints @ Baltimore Ravens
Over 44.5Both of these teams put on a show in Week 1, and I don't see much reason to expect any different in Week 2. Baltimore hung 41 points on Indianapolis behind a fully operational Jackson-Henry combination, while New Orleans and Detroit combined for 61 points in their overtime thriller. That's two offenses trending in the same direction heading into Sunday.
by Luke Lindholm+108odds - NFLwin
New Orleans Saints @ Baltimore Ravens
Spread - New Orleans Saints +6.5New Orleans, meanwhile, is coming off a gut-punch of a Week 1 loss, falling 31-30 in overtime to Detroit after digging itself out of a 21-point hole. That comeback is exactly why I'm not ready to write the Saints off against a number this big.
by Luke Lindholm+106odds - NFLwin
Philadelphia Eagles @ Tennessee Titans
Over 38.5It did not happen last week, but you have to think that Tennessee QB Cam Ward will make some strides in his second year. This is the smallest total (39.5) of the entire week in the NFL.
by Ricky Dimon-106odds - NFLloss
Philadelphia Eagles @ Tennessee Titans
Spread - Philadelphia Eagles -8.5Tennessee opened with a terrible 23-10 home loss to the Jets in Week 1, suggesting that it is the worst team in the entire NFL -- or maybe the second-worst, ahead of Cleveland. Philadelphia (1-0) should roll.
by Ricky Dimon-106odds - NFLloss
Green Bay Packers @ New York Jets
Over 43.5The market is underrating the suddenly competent Jets offense, while the Packers should generate explosives against a questionable New York secondary. Take the over.
by Caleb Wilfinger-108odds - NFLwin
Pittsburgh Steelers @ New England Patriots
Spread - New England Patriots -5Home-field advantage at Gillette Stadium matters here. New England is desperate to avoid an 0-2 start, and I expect a sharper, more disciplined performance from a talented roster that simply beat itself in Week 1. I like the Patriots to clean up the turnovers and cover at home.
by Luke Lindholm-102odds - NFLloss
Cincinnati Bengals @ Houston Texans
Spread - Houston Texans -2.5The Bengals beat the Bucs last week but 24 of their 33 points came off turnovers, and the Texans should bounce back here after coming up just short against the Bills. Houston’s defense allowed the fewest yards per game last season and they should have some success in pacifying Joe Burrow.
by Kevin Rogers-102odds - NFLpush
Green Bay Packers @ New York Jets
Spread - New York Jets +3Jordan Love is a whopping 0-8 against the spread when laying over a field goal on the road and the Jets are much improved following an infusion of talent into this roster over the offseason. Take the home underdog.
by Caleb Wilfinger-102odds - MLB
Miami Marlins @ San Diego Padres
Over 8.5Neither Walker Buehler nor Sandy Alcantara are in good form of late, both displaying issues of their own. Both the Marlins and Padres are crushing right-handed pitching in the last 30 days, and I favor the over in this matchup.
by Javan Shouey+108odds - NFLwin
Philadelphia Eagles @ Tennessee Titans
Over 39.5It did not happen last week, but you have to think that Tennessee QB Cam Ward will make some strides in his second year. This is the smallest total (39.5) of the entire week in the NFL.
by Ricky Dimon-106odds - UFC
D. Figueiredo @ P. Talbott
D. FigueiredoComing Soon
by Pickswise+490odds - MLB
San Francisco Giants @ Los Angeles Dodgers
Under 8.5While the Dodgers offense has been in incredible form as of late, it’s hard to back a side with roughly 90% of public tickets riding the over in this case.
by Ryan Bunnell-102odds - UFC
Dei Pay D. Figueiredo @ P. Talbott
P. Talbottby Pickswise-675odds - NFLloss
Minnesota Vikings @ Chicago Bears
Spread - Chicago Bears -5It could be a classic Week 2 overreaction, but it’s hard to sell what I just saw with the Bears on the road against the NFC South champions. They scored 59 points on the road against the Carolina Panthers, gaining 552 yards and converting 10-of-14 third downs in the process.
by Sam AvelloneEVENodds - MLB
Milwaukee Brewers @ Baltimore Orioles
Under 7.5Read more The Brewers will be send the National League Cy Young favorite to the mound in Jacob Misiorowski. Opposite him, Brandon Young has a 3.65 ERA in 145.2 innings.
by Jon Yaremko+104odds - MLB
Miami Marlins @ San Diego Padres
Over 8Read more Neither Walker Buehler nor Sandy Alcantara are in good form of late, both displaying issues of their own. Both the Marlins and Padres are crushing right-handed pitching in the last 30 days, and I favor the over in this matchup.
by Javan Shouey+108odds - MLB
Minnesota Twins @ Los Angeles Angels
Moneyline - Minnesota TwinsRead more The Angels are baseball's worst lineup against right-handed pitching across the last 30 days, while the Twins have a 106 wRC+ in that span. That difference alone leans me towards the Twins with Dean Kremer and Ryan Johnson scheduled as today's starters.
by Javan Shouey-111odds - MLB
Seattle Mariners @ Colorado Rockies
Moneyline - Colorado RockiesRead more Kade Anderson has not been pitching great recently, as he has given up 10 earned runs across his last 15.1 innings pitched. The Rockies average 4.7 runs per game compared to the Mariners, who are only scoring 4.1 runs per game.
by Jon Yaremko+144odds - MLB
Toronto Blue Jays @ Texas Rangers
Moneyline - Texas RangersRead more Jacob deGrom is in solid form across his last four starts, tossing 24 innings with just four earned runs allowed. Spencer Arrighetti is primed to be the bulk reliever following Spencer Miles as opener, and I am not fond of Arrighetti nor his recent form.
by Javan Shouey-156odds - NFL
Miami Dolphins @ San Francisco 49ers
Miami Dolphins +13.5On a normal week, I could see total domination from San Francisco. However, given the circumstances surrounding this game and the exorbitant price, I would have a very hard time betting someone else’s money on the Niners here, let alone mine.
by Sam Avellone+104odds - NFL
Washington Commanders @ Dallas Cowboys
Dallas Cowboys -4Both teams came up short in Week 1. Dallas struggled on both sides of the ball, while Washington came within a failed two-point conversion of tying its game. Dallas will likely get a boost and a fresh start playing at home, where they have historically performed better overall. I think they learn from their early mistakes and make full use of their home-field advantage come Sunday.
by Aaron Taylor+111odds - NFL
Las Vegas Raiders @ Los Angeles Chargers
Los Angeles Chargers -6.5The Chargers are 5-0 in the previous five meetings with the Raiders at SoFi Stadium, while covering the spread each time. This is a good spot to back the Bolts after their surprising Week 1 loss, as they take on a Raiders team they have owned recently.
by Kevin Rogers-102odds - NFL
Jacksonville Jaguars @ Denver Broncos
Jacksonville Jaguars +2.5The Broncos lost once in eight regular-season home games last season, which came to Jacksonville. The Jags posted a solid 6-2 road mark in 2025, which included blowing a 29-10 lead in a loss at Houston. The expectation is Denver should bounce back, but Jacksonville is playing with plenty of confidence and looks a solid road underdog.
by Kevin Rogers+108odds - NFLwin
Pittsburgh Steelers @ New England Patriots
New England Patriots -5.5Home-field advantage at Gillette Stadium matters here. New England is desperate to avoid an 0-2 start, and I expect a sharper, more disciplined performance from a talented roster that simply beat itself in Week 1. I like the Patriots to clean up the turnovers and cover at home.
by Luke Lindholm+100odds - NFLloss
Minnesota Vikings @ Chicago Bears
Over 47.5If Coach Johnson is serious about breaking the scoring record, explosive plays and tempo are going to be part of the mix. As such, it’s hard not to like the current price on the over.
by Sam AvelloneEVENodds - NFLloss
Minnesota Vikings @ Chicago Bears
Chicago Bears -5It could be a classic Week 2 overreaction, but it’s hard to sell what I just saw with the Bears on the road against the NFC South champions. They scored 59 points on the road against the Carolina Panthers, gaining 552 yards and converting 10-of-14 third downs in the process.
by Sam AvelloneEVENodds - NFL
Cleveland Browns @ Tampa Bay Buccaneers
Cleveland Browns +8Cleveland posted a humiliating effort in Week 1, while Tampa Bay dug themselves too big of a hole to climb out of. In this spot, the public will be all over the Bucs to bounce back, but let’s go with the Browns here getting a shade over a touchdown on the road.
by Kevin Rogers+100odds - NFLwin
New Orleans Saints @ Baltimore Ravens
New Orleans Saints +8.5New Orleans, meanwhile, is coming off a gut-punch of a Week 1 loss, falling 31-30 in overtime to Detroit after digging itself out of a 21-point hole. That comeback is exactly why I'm not ready to write the Saints off against a number this big.
by Luke Lindholm-102odds - NFLloss
Philadelphia Eagles @ Tennessee Titans
Philadelphia Eagles -7Tennessee opened with a terrible 23-10 home loss to the Jets in Week 1, suggesting that it is the worst team in the entire NFL -- or maybe the second-worst, ahead of Cleveland. Philadelphia (1-0) should roll.
by Ricky Dimon+117odds - NFLwin
Carolina Panthers @ Atlanta Falcons
Carolina Panthers -2.5Fortunately for the Panthers, the Falcons' offense won't resemble anything like what the Bears put on the field this past weekend. Atlanta's QB issues are probably too much to overcome.
by Ricky Dimon-108odds - NFLloss
Cincinnati Bengals @ Houston Texans
Houston Texans -2.5The Bengals beat the Bucs last week but 24 of their 33 points came off turnovers, and the Texans should bounce back here after coming up just short against the Bills. Houston’s defense allowed the fewest yards per game last season and they should have some success in pacifying Joe Burrow.
by Kevin Rogers-102odds - NFLwin
Green Bay Packers @ New York Jets
New York Jets +3.5Jordan Love is a whopping 0-8 against the spread when laying over a field goal on the road and the Jets are much improved following an infusion of talent into this roster over the offseason. Take the home underdog.
by Caleb Wilfinger-108odds - UFC
Dei Pay @ D. Figueiredo
Coming Soonby Pickswise+490odds